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Asymptomatic bacteriuria among pregnant women attending antenatal clinic at Kilimanjaro Christian Medical Centre in Northern Tanzania

Moses Kyania Mwei*, Bariki Mchome,Beatrice John and Eusebious Maro

Background: Asymptomatic Bacteriuria (ASB) has been demonstrated to have the adverse maternal and pregnancy outcomes precisely pyelonephritis, low birth weight, preterm premature rupture of membranes and preterm labour. Objective: This study aimed to determine the prevalence of ASB and antibiotic sensitivity pattern among women attending antenatal clinic at Kilimanjaro Christian Medical Centre in Northern Tanzania. Methodology: We conducted analytical cross sectional study involving women attending antenatal clinic at Kilimanjaro Christian Medical Centre between October and December 2016. All women who met the inclusion criteria and gave their informed consent were invited to participate. Interviews using a questionnaire were conducted to collect sociodemographic and obstetric information while urine samples were collected for laboratory processing. Results: The prevalence of ASB among pregnant women in this study was 8.9%. The organism isolated from the urine sample according to the frequency of occurrence was Escherichia coli (50%), Streptococcus pyogenes (19%), Klebsiella pneumoniae (15%), group B Streptococcus (8%) and group A Streptococcus and Proteus mirabilis (4%) respectively. The rate of antibiotic sensitivity among gram negative bacteria ranged from 100% among Escherichia coli and Proteus mirabilis to ceftriaxone while ampicillin was shown to have no sensitivity to Klebsiella pneumoniae and Proteus mirabilis. Among the gram positive bacteria, erythromycin was shown to have sensitivity to group A Streptococcus but no sensitivity to group B Streptococcus. Conclusion: The prevalence of ASB of 8.9% among pregnant women and the wide array of organisms isolated in this population warrant the development of protocols for routine ASB screening and treatment.