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Dutasteride: 21st Century medical therapy for symptomatic benign prostatic hyperplasia

Iqbal S Shergill and Jayanta M Barua

Dutasteride is the latest addition to medical therapy for symptomatic benign prostatic hyperplasia. The safety and efficacy of dutasteride has been firmly established in highquality, randomized, clinical trials, and in this article we discuss these key studies, along with current thoughts on its use in combination with other benign prostatic hyperplasia drugs. The role of dutasteride in chemoprevention of prostate cancer will also be discussed.