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Evolution of adult antiretroviral therapy for programmatic delivery in Africa and the potential role for new therapeutic approaches

Graham S Cooke

Access to antiretroviral therapy (ART) is steadily improving across sub-Saharan Africa. This review discusses the possible evolution of programmatic combination drug therapy and the potential relevance of therapeutic developments, including new classes of antiretrovirals. There are still relatively few published data from resource-poor settings to inform antiretroviral policy, highlighting the need for further research within populations that have the greatest need for treatment.