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Relationship between Digestive Micro ecological Changes and Atherothrombosis

Abdul Hamid

Atherosclerosis (AS) is a chronic inflammatory condition that affects large- and mediumsized arteries. It is the leading cause of Cardiovascular Disease (CVD), which includes ischemic heart disease, strokes, and peripheral vascular disease and has a high mortality rate. Plaque formation in AS is pathological due to lipid infiltration into the vessel wall, endothelial dysfunction, and persistent low-grade inflammation. As of late, an ever increasing number of researchers certainly stand out to the significance of digestive microecological messes in the event and improvement of AS. Digestive G-bacterial cell wall Lipopolysaccharide (LPS) and bacterial metabolites, for example, oxidized Trimethylamine (TMAO) and Short Chain Unsaturated Fats (SCFAs), are engaged with the improvement of AS by influencing the incendiary reaction, lipid digestion, and pulse guideline of the body. In addition, AS progresses more quickly when intestinal microecology interferes with the body’s normal bile acid metabolism. This review provides a summary of the research on the connection between AS and the maintenance of a dynamic balance in intestinal microecology, which may be useful for AS treatment