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Treatment of hypertension in the diabetic patient

Amgad N Makaryus and Samy I McFarlane

Evidence demonstrates that a relationship exists between hypertension, Type 2 diabetes mellitus and several vascular and metabolic abnormalities that are components of the metabolic syndrome. Hypertension associated with the metabolic syndrome and Type 2 diabetes mellitus has pathophysiologic characteristics that provide clinical challenges as well as opportunities for successful therapeutic interventions. This article reviews the treatment of hypertension as a metabolic, as well as a vascular disease, and evaluates the paradigm for the treatment of the diabetic patient population with hypertension.