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Implications of breast cancer with diabetes mellitus on patient outcomes and care

Nina J Karlin, Amylou C Dueck, Sravan K Nagi Reddy, Patricia M Verona & Curtiss B Cook

Aims: The aim of this study was to determine the impact of diabetes mellitus (DM) on short-term overall survival and time to recurrence (TTR) in breast cancer patients, and examine the impact of breast cancer on glycemic control in DM.

Methods: From a data set of newly diagnosed breast cancer patients (2007–2011), we identified 109 patients with DM and 109 matched controls.

Results: Hemoglobin A1c among cases did not significantly change over 1 year (p = 0.10). Cases and controls showed no differences in OS (hazard ratio: 1.25; 95% CI: 0.49–3.17) during the median follow-up of 2.2 years (range: 0.1–4.9 years) and no differences in TTR (hazard ratio: 1.00; 95% CI: 0.14–7.10).

Conclusion: DM did not adversely affect metabolic control, short-term OS or TTR.